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New Base Caller Improves Accuracy of Long
Illumina Reads; May Allow De Novo Assembly

[July 22, 2008]

By Julia Karow

Using Alta-Cyclic, researchers at Cold Spring Harbor Laboratory were able to increase the number of accurate 78-base reads in a run from 5 percent to 22 percent. These reads, they say, may allow them to assemble complex eukaryotic genomes de novo.

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